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ArticlesCordyceps CS-4 research

 
 

Cordyceps CS-4 mushroom mycelia research



Used in traditional medicine
since the Ming Dynasty

Cordyceps Sinensis, sometimes known as "Caterpillar Mushroom" in North America, is a highly valued medicinal mushroom in traditional Chinese medicine, used to treat "lung" and "kidney" asthenia, heart disease and fatigue1.

The most outstanding work on traditional Chinese medicines "Ben Cao Gang Mu" (Compendium of Materia Medica) was published by Li Shi-Zhen in 1578 during the Ming Dynasty.

"Ben Cao Gang Mu" documented more than twenty mushroom species including Codyceps which was recorded as "Snow Silkworm"2.

The name reflected the wormlike shape of the mushroom and the fact that Cordyceps Sinensis grows primarily on the Tibetan plateau above 12,000 feet, close to the snow line3.

About CS-4
(Paecilomyces hepiali C.)

Natural Cordyceps Sinensis is extremely rare4 It has a 6 year life-cycle which makes it very expensive5. This exorbitant cost led Chinese researchers to develop a technique for isolating a fermentable strain from wild Cordyceps Sinensis called CS-4 (Paecilomyces hepiali C)6.

 

Cordyceps Sinensis, sometimes known as "Caterpillar Mushroom" in North America, is a highly valued medicinal mushroom in traditional Chinese medicine, used to treat "lung" and "kidney" asthenia, heart disease and fatigue1.

This is used to produce a fermented mycelia
7 product that contains pharmacologically active components similar to the wild Cordyceps Sinensis including cordycepic acid (D-mannitol), adenosine8, and polysaccharides9.

 
 

Other Cordyceps species
cannot produce CS-4

 

Scientific research has conclusively proven that Cordyceps Sinensis (CS-4) as a particular species is unable to be artificially cultured for its mushroom
fruit body.

Commercial products claiming to be from cultured natural Cordyceps mushrooms are in fact not from

 

Cordyceps Sinensis, but another species called Cordyceps Militaris (see the picture on the left). Cordyceps Militaris is found in wild in North China, close to Korea.

Active compounds

Modern research on Cordyceps Sinensis in relation to lung, kidney and immune system10,11disorders highlights that the active compounds in Cordyceps Sinensis are polysaccharides12, mannitol (cordycepic acid)13, and adenosine14.

 
 

Always seek medical advice

Information provided on this website is provided for information purposes only and is not intended to replace advice from a qualified medical practitioner. For information about medical conditions please consult your doctor.

 

Cordyceps CS-4 original research

As the leader in standardised mushroom extracts we believe passionately in sharing information from the growing body of published research on medicinal mushroffoms. This is for education purposes only and Mycopharmaź cannot and does not vouch for the accuracy of independent research. To make your own informed decisions please refer to the original published research about Cordyceps CS-4.

 
 
 
1.LINGHUA Z., PEIGENG X., CHINESE TRADITIONAL HERBS, 1992, 23(2): 95-99
2.TINGBAO L., CHINESE TRADITIONAL HERBS, 1981, 12:525
3.4.5.GE Y., AMINO-ACIDS AND BIOLOGICAL RESOURCES, 1997, 19(3): 35-37
6.XIJIN L. ET AL. NEWSLETTER OF MYCOLOGY, CHINA. 1989,06
7.YUNQUAN S. ET AL. RESEARCH SUMMARY OF CORDYCEPS MYCELIA CULTIVATION, AVISO OF TRADITIONAL CHINESE
MEDICINNE, 1985,10(12): 3-5
8.GENGTAO L., IMMUNOLOGICAL CLINICAL EFFECT OF CORDYCEPS SINENSIS, JOURNAL OF COMBINATION OF WESTERN MEDICINE AND TRADITIONAL CHINESE MEDICINE 1985, (5): 622
9.LI Z., NUTRITION RESEARCH OF CORDYCEPS SINENSIS, AVISO OF PHARMACEUTICS, 1988, 23(9): 524
10.GEORGES M. HALPERN: CORDYCEPS, CHINESE HEALING MUSHROOM, A VERY PUBLISHING, 1999.
11.J.ZHU, G.M. HALPERN AND K.JONES: THE SCIENTIFIC REDISCOVERY OF AN ANCIENT CHINESE HERBAL MEDICINE: CORDYCPES
SINENSIS, ALTERNATIVE AND COMPLEMENARY THERAPIES, 4(3-4), 289-303, 429-457
12.GENGTAO L., IMMUNOLOGICAL CLINICAL EFFECT OF CORDYCEPS SINENSIS, JOURNAL OF COMBINATION OF WESTERN MEDICINE
13.14.LI Z., NUTRITION RESEARCH OF CORDYCEPS SINENSIS, AVISO OF PHARMACEUTICS, 1988, 23(9): 524
   
 
   
 
         
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