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ArticlesReishi research

 
 

Reishi mushroom research



Active constituents beta D-glucans, triterpenoids   Active constituents
beta D-glucans, triterpenoids

Mushroom beta-D-glucan diagram   View detailed Reishi triterpenoids diagram1


Reishi contain beta-D-glucan2 which is believed to be the key to Reishi's immune stimulating properties linked to beta-glucans receptors found on neutrophils3, monocytes or macrophages4, NK cells5, and T and B lymphocytes6.

Reishi also contain triterpenoids. These triterpenoids (including ganoderic acid) promote immune response in the body7.

Traditional use

As a royal herb of ancient China and "mushroom of immortality", Reishi has been used as a medicinal mushroom in China and other Asian countries for 2,000 years.

Pharmacological and clinical research

As a supplement for cancer patients, Reishi can reduce side-effects of cytotoxic cancer therapy or radiotherapy8, and reduce the pain9.

It also has significant efficacy on anti-fatigue10, hair loss11, and bone marrow suppression12.

When used as a supplement for cancer patients, the recommended daily dose is 5-10 grams of Reishi mushroom extract or equivalent13.

Reishi triterpenes are found to inhibit cholesterol synthesis, reduce hypertension, protect the liver and have antioxidant properties14.

 

As a royal herb of ancient China and "mushroom of immortality", Reishi has been used as a medicinal mushroom in China and other Asian countries for 2,000 years.

Always seek medical advice

Information provided on this website is provided for information purposes only and is not intended to replace advice from a qualified medical practitioner. For information about medical conditions please consult your doctor.

Reishi original research

As the leader in standardised mushroom extracts we believe passionately in sharing information from the growing body of published research on medicinal mushrooms. This is for education purposes only and Mycopharmaź cannot and does not vouch for the accuracy of independent research. To make your own informed decisions please refer to the original published research about Reishi.

 
 
1.RUOYUN CHEN, DEQUAN YU, ET AL. RESEARCH DEVELOPMENT OF THE CHEMICAL COMPOUNDS FOUND IN REISHI: TRITERPENOIDS, ACTA PHARMACEUTICA SINICA 1990; 25(12): 940-953
2.
JOHN E. SMITH ET AL, MEDICINAL MUSHROOMS: THEIR THERAPEUTIC PROPERTIES AND CURRENT MEDICAL USAGE WITH SPECIAL EMPHASIS ON CANCER TREATMENTS; EXTRACTION, DEVELOPMENT AND CHEMISTRY OF ANTI-CANCER COMPOUNDS FROM MEDICINAL MUSHROOMS, CHAPTER 5, P80.
3.MORIKAWA K., T R., YAMAZAKI M. AND MIZUNO D. INDUCTION OF TUMORCIDAL ACTIVITY OF POLYMORPHONUCLEAR LEUKOCYTES BY A LINEAR-1,3-D-GLUCAN AND OTHER IMMNO-MODULATORS IN MURINE CELLS. CANCER RES. 45:1496-1501 (1985).
4.CZOP J.K., AND KAY J. ISOLATION AND CHARACTERIZATION OF B-GLUCAN RECEPTORS ON HUMAN MONOUCLEAR PHAGOCYTE. J.EXP. MED. 173:1511-1520(1991)
5.DI RENZO L.,YEFENOF E., AND KLEIN E. THE FUNCTION OF HUMAN NK CELLS IN ENHANCED BY B-GLUCAN, A LIGAND OF CR3(CDIIB/CD18). EUR.J.IMMUNOL.21:1755-1785(1991)
6.GOTOH K., GOUCHI A.,AKURA Y., TANAKA N. AND ORITA K, AUGMENTATION OF CYTOTOXICITY OF TUMOR-INFILTRATING LYMPHOCYTES BY BIOLOGICAL RESPONSE MODIFIERS. INT. J. IMMUNOPHARMAC. 5:485-492,1991.
7.KIM H.W. AND KIM B.K. 1999. BIOMEDICAL TRITERPENOIDS OF GANODERMA LUCIDUM (CURT.:FR.) P.KARST. (APHYLLOPHOROMYCETIDEAE).INT J MED MUSHR,1,121-138.
8.THULASI ET AL. POLYSACCHARIDES ISOLATED FROM GANODERMA LUCIDUM, PROTECTS RADIATION INDUCED DAMAGES BOTH IN VITRO AND IN VIVO. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2008; 26(1), 80-85.
9.KUPIN, V. (1994) A NEW BIOLOGICAL RESPONSE MODIFIER - GANODERMA LUCIDUM - AND ITS APPLICATION IN ONCOLOGY. IN PROCEEDINGS FROM THE 6TH INTERNATIONAL SYMPOSIUM ON GANODERMAN LUCIDUM. SEOUL, II YANG, P.36-37.
10.YANG, Q.Y. ET AL. (1995) THE EFFECT OF GANODERMA LUCIDUM EXTRACT AGAINST FATIGUE AND ENDURANCE IN THE ABSENCE OF OXYGEN. IN PROC. CONTRIBUTED SYMPOSIUM. 59A, B.2. ROLE OF GANODERMA SUPPMENTATION IN CANCER MANAGEMENT.
11.MIYAMOTO,T., ABE,T., HASUNUMA,K.(1985). JAPAN KOKAI TOKYO KOHO JP60, 199,80 [85,199.810] (CI.A61K7/06). APPL. 84/5,977. 24 MAR. 1984.
12.JIA, ET AL. EFFECTS OF LING-ZHI ON HEMOPOIETIC SYSTEM IN MICE IMMUNOPHARMACOLOGICAL STUDY (11). IN THE RESEARCH ON GANODERMA (PART I). ZHU S. AND MORI M. (EDS). SHANGHAI MEDICAL UNIVERSTIY PRESS, SHANGHAI, P.284-288.
13.CHANG, R. (1994) EFFECTIVE DOSE OF GANODERMA IN HUMANS. IN PROC. CONTRIBUTED SYMPOSIUM 59A, B. 5TH INTL. MYCOL. CONGR., BUCHANAN PK, HSEU RS AND MONCALVO JM (EDS), TAIPEI, P. 101-13.
14.ZHU ET AL. (1999) TRITERPENE ANTIOXIDANTS FROM GANODERMA LUCIDUM. PHYTOTHER RES 13, 529-531.
 
 
   
 
         
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